It is my pleasure to welcome you on this website.
This website is thought to be a source of information for all those seeking information regarding my former and present activities or who are looking for consultation and support in the field of R&D Management (toxicology, non-clinical/preclinical safety, chemical safety, quality management). You will find information on who I am, on what I did in the past and on what keeps me busy at present. I’d be happy if I could be of help also for you.
I hope you will find this website attractive and interesting, and of course I welcome any feedback or proposal for any improvement.
Non-Clinical Drug Safety & Safety Evaluation Industrial Chemicals/Cosmetics)
Non-Clinical Drug Safety approaches (toxicology and safety pharmacology) support clinical studies and the approval of new drugs.
Still today is true:
“What is there that is not poison? All things are poison and there is nothing without poison. Solely the dose determines that a thing is not a poison.” (Paracelsus 1493 – 1541)Read more
Alternative Methods in Toxicology
Researchers are obliged to examine thoroughly each case and to make sure that the scientific goals cannot be achieved with alternative methods (§ 7 Abs. 2 TierSchG).Read more
R&D Management Consulting – Quality
What makes a successful conflict resolver (R&D manager) are not specific processes, methodologies, ot tactics; it is a way of thinking, a set of values, an array of analytical and interpersonal skills, and a clear focus.
If other parameters instead of high quality get first priorities then success becomes a matter of luck.Read more
During the last decade the use of water has been reconsidered all over the world and also in this field the idea of sustainability has found its way.
Many countries, cities and small towns try hard to make their contribution. Keywords like stream restoration, daylighting of streams, separation of sewerage system and clean water (incl. rainwater), and improvement of quality of life for urban and rural citizens are typical when discussing this subject.Read more
Here you can find a Selection of my Publications.
Regulatorische Toxikologie: Grundzüge, Testverfahren und Einrichtungen K.E. APPEL, U. GUNDERT-REMY UND P. KRAMER, BERLIN UND DARMSTADT ##Lehrbuch-Artikel aus "Toxikologie" 3. Auflage 2013 Inhalt in Stichworten: 1. Historischer Rückblick 2. Prinzipielle...
Critical evaluation of key evidence on the human health hazards of exposure to bisphenol A CRITICAL REVIEWS IN TOXICOLOGY, 2011; 41(4): 263–291 For more than 10 years there has been a scientific and journalistic controversy whether bisphenol A (BPA) causes...